Control kif13b tail

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WebOct 20, 2024 · Kif13b iECKO had a markedly decreased rate of lung metastasis compared to the WT control. N = 18, 16 for Kif13b WT and Kif13b iECKO, respectively. (E) … WebJan 26, 2015 · In cells that expressed KIF13B 442–831 tail and were treated with the linker drug, there was no change in the localization of TfR-GFP vesicles. In cells expressing KIF13B 832–1,826 tail, addition of the linker drug resulted in a pronounced redistribution of TfR-GFP to the cell center.

KIF13B erects an endocytic scaffold Journal of Cell Biology ...

WebControl of Motor Landing and Processivity by the CAP-Gly Domain in the KIF13B Tail Preprint Full-text available Aug 2024 Xiangyu Fan Richard J. McKenney Microtubules … http://bcz102.ust.hk/publications/2016/2016_Structure_An%20Atypical%20MAGUK%20GK%20Target%20Recognition%20Mode%20Revealed%20by%20the%20Interaction%20between%20DLG%20and%20KIF13B.pdf pop up iphone has been compromised

KIF13B-mediated VEGFR2 trafficking is essential for vascular …

WebKif13b (a.k.a. 5330429L19Rik, 6030414C01, C130021D12Rik, GAKIN) Promoter Chicken Beta actin Cloning Information Cloning method Restriction Enzyme 5′ cloning site … WebAug 31, 2024 · The tail of KIF13B has multiple domains for cargo-binding. Besides VEGFR2, KIF13B transports polarity determination factors such as PIP3. These cargoes bind distinct regions of KIF13B often by bridge proteins such as Centaurin-α. WebEach KIF13B Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our KIF13B Antibodies can be used in a variety … popup is not defined react/jsx-no-undef

KIF13B establishes a CAV1-enriched microdomain at …

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Webcilia to control their composition8,9. Consequently, mutations ... KIF13B tail region contains two RPGRIP1N-C2 type domains. To delineate the minimal polypeptide portion required for 6 ac DIC * d ... WebKIF13B is upregulated during ciliogenesis and is recruited to the ciliary base by NPHP4, which binds to two distinct sites in the KIF13B tail region, including an RPGRIP1N-C2 domain. KIF13B and NPHP4 are both essential for establishment of a CAV1 membrane microdomain at the TZ, which in turn is required for Shh-induced ciliary SMO accumulation. popup isopenWebApr 25, 2024 · 1) KIF13A localizes to a variety of tubular endosomes and mediates cargo recycling and transport to maturing melanosomes. 2) KIF13A forms homodimers or heterodimers with KIF13B on early/sorting endosomes and generates recycling endosomes. 3) KIF13A motor activity modulates the membrane dynamics (length and number) of … popup is requested for

"WebKIF13B and NPHP4 are both essential for establishment of a CAV1 membrane microdomain at the TZ, which in turn is required for Shh-induced ciliary SMO accumulation. Thus … " - Control kif13b tail

Control kif13b tail

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Web6811B/6812B/6813B User's Guide. This User's Guide is for use with the following Keysight model and serial numbers: Model 6811B: US38390101 and Above Model 6812B: … WebAug 3, 2024 · We tested the system by expressing KIF5Cmd, which was fused to an FKBP domain and mRFP, and either KIF1Atd or KIF13Btd in cultured hippocampal neurons in two different conditions, one without rapalog and one where rapalog was added to the culture medium directly after transfection.

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Webitself control KIF13B expression. To addressthe roleofKIF13Bin ECsin vivo,wegenerated micein which KIF13B was conditionally deleted in the endothelium. Kif13b- ... injected via the tail vein to assess lung metastasis in Kif13bWT and Kif13biECKO. 2 wk after injection, lungs were isolated, and metastatic foci were counted (Fig 4C–E). WebAug 11, 2024 · Control of Motor Landing and Processivity by the CAP-Gly Domain in the KIF13B Tail. Fan X ...

WebJan 30, 2024 · KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Ciliary membrane composition is … WebAug 11, 2024 · KIF13B is a member of the long-distance transport kinesin-3 family, and the only kinesin motor that contains a conserved C-terminal CAP-Gly domain. What role the CAP-Gly domain plays in...

WebMay 26, 2024 · Our free 2-year warranty makes every Radwell purchase a dependable, reliable investment in your company's future. Warranty Terms and Conditions. If you … WebNov 21, 2024 · KIF13B contains an N-terminal MD, a neck domain (containing the NL and NC), a CC1-FHA-CC2 tandem followed by a MBS domain, and a C-terminal CAP-Gly domain. The residue numbers for each domain are indicated below the domain organization.

WebMar 1, 2024 · KIF13A/B are novel Rab10-interacting proteins Since Rab proteins are generally thought to regulate membrane trafficking through …

WebGene: Kif13b MGI:1098265 Gene Summary Name: kinesin family member 13B Synonyms: N-3 kinesin, C130021D12Rik, 5330429L19Rik, GAKIN Order Alleles IMPC Data Collections Body Weight Measurements No Embryo Imaging Data No Viability Data IMPC Phenotype Summary Significant Not Significant Not tested View all our phenotype data below … sharon martinez monroe ctWebAug 11, 2024 · Here, we investigated the interaction between KIF13B’s CAP-Gly domain, and the tyrosinated C-terminal tail domain of α-tubulin. We found that KIF13B’s CAP … sharon martin law and orderWebWe studied KIF13B because it is a nonmitotic kinesin essential for transport of molecules in nondividing mature cells.20 These kinesins regulate the trafficking of specific signaling … popup is blocked in chromeWebVEGFR2 coimmunoprecipitated with KIF13B in control cells, ... (PBS), i.v. via tail vein, three times per week, and tumor size is shown in the graph. B and C: Number of vessels in tumor in PBS-treated control and peptide-treated tumor. Representative immunohistochemistry of VEGFR2 and von Willebrand factor (vWF) are shown to … pop up invitation birthday cardWeb‎The Tail Company makes amazing animatronic gear that brings life to your Cosplay or Fursona. MiTail is our super expressive animatronic tail and EarGear are our new moving ears! This app is the brains behind all your Tail Co gear, including EarGear, MiTail and DIGITAiL! Control Moves, create Move… sharon martin les feldick ministries pop up iron sights front sightWebबाल हनुमान की नटखट पूंछ क्यों कर रही है उनको परेशान महाबली हनुमान भाग.37Hanuman ... sharon martino